HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Submit a response Alert me when this article is cited Alert me when Rapid Responses are posted Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Bishop, B. Search for Related Content PubMed PubMed Citation Articles by Bishop, B. Related Collections Related Article

Pain: Its Physiology and Rationale for Management: Part I. Neuroanatomical Substrate of Pain

Dr. Bishop is Professor of Physiology, Department of Physiology, School of Medicine, State University of New York at Buffalo, Buffalo, NY 14214.

Pain, one of man's most worrisome afflictions, is also one of neurobiology's most challenging problems. Even its definition is beset with controversy. The origin and current resolution of this controversy are presented in this paper, but the major purpose of Part I is to review the anatomical substrate of the peripheral and central nervous systems involved in pain. Structural and functional characteristics of pain receptors and their afferent fibers are described, with emphasis upon current hypotheses regarding putative neural transmitters and possible mechanisms for signal transduction. Hitherto unrecognized details of the cytoarchitecture, anatomical organization, and circuitry of the dorsal horns are reviewed. The paper concludes with a consideration of the major components of the ascending and descending systems of subserving pain.

Key Words: Neuroanatomy • Neurophysiology • Pain

Related Article

Pain

Beverly Bishop
Physical Therapy 1980 60: 219. [Abstract] [PDF]