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Research Reports |
SA Norman, PhD, is Research Associate Professor, Department of Biostatistics and Epidemiology, 801 Blockley Hall, 423 Guardian Dr, University of Pennsylvania, Philadelphia, PA 19104-6021 (USA) (snorman{at}cceb.med.upenn.edu).
LT Miller, PT, BS, BA, is Clinical Director, Breast Cancer Physical Therapy Center, Philadelphia, Pa
HB Erikson, PT, BS, BA, is Physical Therapist, Penn Therapy and Fitness, Hospital of the University of Pennsylvania, Philadelphia, Pa
MF Norman, PhD, is Professor, Department of Psychology, University of Pennsylvania, Philadelphia, Pa
R McCorkle, RN, PhD, is Professor, School of Nursing, Yale University, New Haven, Conn
Address all correspondence to Dr Norman
Background and Purpose. Accurate and economical characterization of lymphedema is needed for population-based studies of incidence and risk. The purpose of this study was to develop and validate a telephone questionnaire for characterizing lymphedema. Subjects. Forty-three women who were treated previously for breast cancer and who were recruited from physical therapy practices and a cancer support organization were studied. Methods. Questionnaire assessment of the presence and degree of lymphedema was compared with physical therapists' diagnoses, based primarily on circumferential measurements. Twenty-five of the 43 subjects were measured independently by 2 physical therapists to assess interobserver agreement. Results. Interobserver agreement on clinical assessments of the presence and degree of lymphedema was high (20/25, weighted kappa=.80); all of the disagreements were between judgments of whether there was no lymphedema or mild lymphedema. For the diagnosis of at least moderate lymphedema (differential in the circumferences of the upper extremities greater than 2 cm), sensitivity of the questionnaire varied from 0.86 to 0.92 and specificity was 0.90. However, sensitivity (varying from 0.93 to 0.96) was higher than specificity (varying from 0.69 to 0.75) for the diagnosis of any lymphedema. Discussion and Conclusion. A few straightforward questions exhibited excellent agreement with physical therapists' assessments for identifying at least moderate lymphedema.
Key Words: Breast neoplasms Health status Lymphedema Questionnaires
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R. L. Ahmed, W. Thomas, D. Yee, and K. H. Schmitz Randomized Controlled Trial of Weight Training and Lymphedema in Breast Cancer Survivors J. Clin. Oncol., June 20, 2006; 24(18): 2765 - 2772. [Abstract] [Full Text] [PDF] |
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